Yukio Homma Selected Research

Interstitial Cystitis (Interstitial Cystitis, Chronic)

3/2022	Cystectomy for patients with Hunner-type interstitial cystitis at a tertiary referral center in Japan.
1/2022	Overexpression of HIF1α in Hunner Lesions of Interstitial Cystitis: Pathophysiological Implications.
1/2021	Relationship between the frequency of electrocautery of Hunner lesions and changes in bladder capacity in patients with Hunner type interstitial cystitis.
1/2021	Efficacy and safety of intravesical instillation of KRP-116D (50% dimethyl sulfoxide solution) for interstitial cystitis/bladder pain syndrome in Japanese patients: A multicenter, randomized, double-blind, placebo-controlled, clinical study.
1/2021	Autoimmunity to urothelial antigen causes bladder inflammation, pelvic pain, and voiding dysfunction: a novel animal model for Hunner-type interstitial cystitis.
1/2019	Suplatast tosilate in patients with interstitial cystitis: Efficacy and treatment possibilities, with suggestions for future assessments.
1/2019	Molecular Taxonomy of Interstitial Cystitis/Bladder Pain Syndrome Based on Whole Transcriptome Profiling by Next-Generation RNA Sequencing of Bladder Mucosal Biopsies.
1/2019	Editorial Comment from Dr Homma to Intravesical tacrolimus in treatment of intractable bladder pain syndrome/interstitial cystitis-a pilot study.
1/2018	Diagnostic value of urinary CXCL10 as a biomarker for predicting Hunner type interstitial cystitis.
1/2017	Toll-like receptor 7 is overexpressed in the bladder of Hunner-type interstitial cystitis, and its activation in the mouse bladder can induce cystitis and bladder pain.

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Yukio Homma Research Topics

Disease

60	Neoplasms (Cancer) 01/2021 - 05/2004
54	Prostatic Neoplasms (Prostate Cancer) 01/2019 - 04/2004
22	Carcinoma (Carcinomatosis) 11/2018 - 03/2012
21	Overactive Urinary Bladder (Overactive Bladder) 12/2019 - 05/2005
19	Interstitial Cystitis (Interstitial Cystitis, Chronic) 03/2022 - 10/2007
17	Neoplasm Metastasis (Metastasis) 09/2017 - 05/2004
15	Renal Cell Carcinoma (Grawitz Tumor) 04/2020 - 01/2009
12	Prostatic Hyperplasia (Benign Prostatic Hyperplasia) 09/2018 - 06/2004
12	Urinary Bladder Neoplasms (Bladder Cancer) 02/2018 - 03/2002
6	Lower Urinary Tract Symptoms 01/2019 - 11/2006
6	Testicular Neoplasms (Testicular Cancer) 04/2016 - 04/2005
5	Pain (Aches) 01/2021 - 09/2006
5	Inflammation (Inflammations) 01/2021 - 01/2017
5	Urinary Incontinence 01/2019 - 06/2011
4	Urinary Bladder Neck Obstruction (Bladder Neck Obstruction) 01/2018 - 07/2011
3	Hypersensitivity (Allergy) 01/2021 - 05/2016
3	Carcinogenesis 04/2020 - 06/2004
3	Hydronephrosis 10/2017 - 03/2006
3	Insulin Resistance 03/2017 - 05/2011
3	Hypertension (High Blood Pressure) 03/2017 - 03/2015
3	Metabolic Syndrome (Dysmetabolic Syndrome X) 03/2017 - 03/2015
3	Small Cell Carcinoma 01/2017 - 01/2016
3	Nocturia 10/2016 - 01/2002
3	Urinary Retention 03/2015 - 02/2009
3	Adenocarcinoma 01/2015 - 06/2004
3	Disseminated Intravascular Coagulation 12/2013 - 12/2012
3	Body Weight (Weight, Body) 05/2013 - 02/2011
2	Fibrosis (Cirrhosis) 01/2021 - 10/2010
2	Pelvic Pain 01/2021 - 04/2017
2	Hypogonadism (Hypergonadotropic Hypogonadism) 01/2018 - 11/2014
2	Germ Cell and Embryonal Neoplasms (Germ Cell Tumor) 01/2018 - 01/2013
2	Kidney Neoplasms (Kidney Cancer) 03/2017 - 03/2010
2	Melanoma (Melanoma, Malignant) 01/2017 - 04/2016
2	Urologic Neoplasms (Urological Cancer) 01/2017 - 06/2014
2	Infections 12/2016 - 07/2013
2	Polyuria 10/2016 - 09/2013
2	Lymphatic Metastasis 02/2016 - 09/2012

Drug/Important Bio-Agent (IBA)

20	AndrogensIBA 11/2018 - 05/2004
11	Androgen Receptors (Androgen Receptor)IBA 01/2019 - 03/2012
8	Proteins (Proteins, Gene)FDA Link 04/2020 - 12/2010
8	Biomarkers (Surrogate Marker)IBA 01/2018 - 03/2010
8	silodosin FDA Link 01/2018 - 11/2006
7	Hormones (Hormone)IBA 01/2019 - 09/2006
6	AntigensIBA 01/2021 - 06/2013
6	mirabegronIBA 12/2019 - 12/2012
6	imidafenacinIBA 05/2017 - 09/2008
6	Docetaxel (Taxotere)FDA Link 04/2016 - 12/2011
5	Messenger RNA (mRNA)IBA 01/2021 - 10/2007
5	Muscarinic AntagonistsIBA 01/2019 - 02/2009
5	Prostate-Specific Antigen (Semenogelase)IBA 05/2018 - 05/2004
5	Cholinergic Antagonists (Anticholinergics)IBA 10/2017 - 10/2009
5	Cisplatin (Platino)FDA LinkGeneric 10/2017 - 09/2013
5	Estrogens (Estrogen)FDA Link 01/2016 - 03/2010
5	CreatinineIBA 11/2014 - 05/2002
4	Biological ProductsIBA 01/2022 - 01/2013
4	C-Reactive ProteinIBA 09/2017 - 05/2011
4	Tamsulosin (Flomax)FDA LinkGeneric 12/2013 - 02/2006
3	SolutionsIBA 01/2021 - 11/2013
3	RNA (Ribonucleic Acid)IBA 01/2019 - 01/2016
3	Testosterone (Sustanon)FDA Link 01/2018 - 04/2005
3	Long Noncoding RNAIBA 03/2017 - 06/2013
3	Insulin (Novolin)FDA Link 03/2017 - 03/2015
3	SodiumIBA 03/2017 - 03/2015
3	Pharmaceutical PreparationsIBA 01/2017 - 03/2002
3	Hemoglobins (Hemoglobin)IBA 01/2017 - 11/2014
3	Type A Botulinum Toxins (Botox)FDA Link 09/2015 - 06/2011
3	Transcription Factors (Transcription Factor)IBA 02/2015 - 04/2011
3	DNA (Deoxyribonucleic Acid)IBA 12/2014 - 07/2009
3	Tyrosine Kinase InhibitorsIBA 11/2014 - 01/2011
3	Cholinergic Agents (Cholinergics)IBA 04/2014 - 09/2008
3	Indicators and Reagents (Reagents)IBA 01/2014 - 09/2011
3	Adrenergic Receptors (Adrenergic Receptor)IBA 12/2013 - 12/2010
2	Immunoglobulin G (IgG)IBA 01/2021 - 04/2014
2	LipopolysaccharidesIBA 01/2021 - 10/2018
2	Peptides (Polypeptides)IBA 01/2019 - 02/2012
2	CytokinesIBA 01/2019 - 01/2018
2	ChemokinesIBA 01/2018 - 03/2010
2	Amyloid (Amyloid Fibrils)IBA 01/2018 - 01/2013
2	Alkaline PhosphataseIBA 01/2017 - 05/2011
2	AlbuminsIBA 01/2017 - 02/2016
2	Gemcitabine FDA Link 01/2016 - 12/2010
2	Etoposide (VP 16)FDA LinkGeneric 01/2016 - 10/2012

Therapy/Procedure

33	Therapeutics 01/2019 - 04/2004
20	Prostatectomy (Retropubic Prostatectomy) 03/2022 - 04/2004
19	Drug Therapy (Chemotherapy) 05/2020 - 03/2002
14	Cystectomy 03/2022 - 01/2013
13	Nephroureterectomy 10/2017 - 03/2006
12	Nephrectomy 04/2020 - 01/2009
6	Intravesical Administration 01/2021 - 03/2002
6	Castration 01/2019 - 01/2012
6	Radiotherapy 06/2017 - 09/2014
5	Immunotherapy 01/2017 - 03/2006
4	Orchiectomy (Orchidectomy) 11/2016 - 09/2011
3	Nephrotomy 03/2022 - 03/2006
3	Catheters 05/2017 - 10/2012
3	Oncolytic Virotherapy 01/2017 - 01/2010
2	Neoadjuvant Therapy 02/2018 - 04/2015
2	Adjuvant Chemotherapy 10/2017 - 04/2015
2	Urinary Diversion (Ileal Conduit) 04/2017 - 12/2014
2	Peritoneal Dialysis 12/2016 - 11/2014